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During the last stage of menstrual cycle, normally a layer of endometriosis lining in the inside of uterus is expelled which is known as menstruation blood, but instead some of the endometriosis tissues grow somewhere in the body causing endometriosis. They also react to hormone signals of the monthly menstrual cycle, building up tissue, breaking it and eliminating it through the menstrual period. In this article, we will discuss what causes endometriosis. In fact, the causes of endometriosis are not known, but there are some suggestions and theories.
I. Inflammation
1. Retrograde menstruation
Retrograde menstruation means that during menstruation, blood flows backwards instead of forwards causing menstrual blood to go through the fallopian tubes and gain access to the pelvic and abdominal cavity, resulting in inflammation. Endometrial lining sheds now may attach to the abdominal region forming implants or adhesion if the body's defenses cannot get rid of them.
2. Weakened immune system
Endometrial lining can grow anywhere in our body such as the pelvic area, on the fallopian tube, ovaries, and bladder. It is the responsibility of our body to destroy them, otherwise the endometrial lining may cause endometrial implants and adhesion attaching to the organ causing inflammation and damage to the organs. Weakened immune system and nervous system are caused by excessive drinking resulting in liver disease or nutritional deficiency, as a resulting of unhealthy diet.
3. Overproduction of xanoestrogen
Xenoestrogens are parts of a heterogeneous group of chemicals that are a hormonally active agent. Xenoestrogens as false messengers that disrupt the process of reproduction, causing inflammation, and increase growth of endometrium.
4. Environment toxins
Study shows that the average human body absorbs hundred of synthetic chemicals from the environment everyday such as insecticides, herbicides, gasoline, and household cleaning products. This causes uncontrolled cellular growth of free radicals as well as endometrial inflammation if the defense system which cannot destroy them through normal processes. Endometriosis implants and adhesion are the result.
5. Liver diseases
The liver is the first line of our defense system. It secretes bile to the intestine that helps to destroy any foreign substance that enters our body through intake of food. If the liver is weakened, endometrial lining may be attached to the intestine wall or on the surface of the liver causing inflammation as well as endometrial implants or adhesion.
II. Coelomic metaplasia
1. Retrograde menstruation
As blood flows backwards instead of forwards through the fallopian tube and gains access to the pelvic and abdominal cavity, it causes internal infection or inflammation of organs inside the abdominal region, resulting in transformation of some peritoneal cells into endometrial cells attached in the abdominal wall.
2. Inflammation
It is possibile that infection of bacteria, parasites or virus such as salmonellae caused inflammation of some cells of the peritoneum resulting in coelomic metaplasia.
3. Iatrogenic origin
It is said that during medical surgery, some cells from the internal wall of the uterus might be accidentally transferred to the abdominal cavity and become endometrial adhesion or implants attached to the organ in the abdominal cavity.
4. Xenoestrogen overload
Xenoestrogen is the bad estrogen entering our body from the foods we eat everyday. They are by-products of manufacturing processes. During the surge of estrogen at the beginning of menstrual cycle, over-production of xenoestrogen causes hormone imbalance resulting in over-stimulation of certain hormones, causing some of the cells of the peritoneum developing into endometrial cells.
5. Environment toxins
Our body works it's best to cope with hundreds of synthetic chemicals everyday, if any thing goes wrong during this process, free radicals form as well as increasing the risk of some of the cells of the peritoneum to develop into endometrial cells. Study shows that over-exposure to dioxin and certain types of waste incineration increase the risk of endometriosis.
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III. Congenital or embryonic rest
1. Hormonal imbalance
During the embryonic stage, if the mother has a sudden surge of estrogen or high estrogen levels for a prolonged period of time causing low levels of progesterone that is necessary for nourishing the fetus resulting in defection of cell development. Some of the endometrial cells may develop irregularly in the abdomen.
2. Hormonal stimulating medication
There are some women taking hormonal stimulating medication to influence the hormone system to produce certain hormones, resulting in hormonal imbalance or abnormal cellular development during pregnancy stages. Over-production of estrogen may influence the irregular development of endometrial cells in the wrong place in abdomen area or miscarriage.
3. Environment factor
Synthetic chemicals such as insecticides, herbicides, gasoline fumes, and food packaging is harmful to the human body. If pregnant women come in contact with these types of toxins for prolonged periods of time, it not only causes weakening of immune system but also surging of certain types of hormones resulting in malfunction of cells development in the fetus. If such malfunction is endometriosis-related then it may influence irregularly the development of endometrial cells other than in the endometrium.
4. Xenoestrogen
Unhealthy diet during pregnancy with intake of xenoestrogen-promoting foods for a prolonged period of time causes overproduction of harmful estrogen that stimulates the irregular endometrial cell development resulting in endometriosis.
5. Congenital defects
Congenital defects such as cervical stenosis, the lack of opening in the hymen or other congenital abnormalities causing menstrual blood retention in the uterus or retrograde menstruation that allows endometrial cells to implant in the abdominal region.
IV. Xenoestrogen
1. Environment toxins.
Our body tries to get rid of environmental toxins everyday through our liver and digestive system. Environmental toxins may come from food intake, air that we breath, or contact through skin. Overdosing of these types of toxins cause hormonal imbalance resulting in xenoestrogens disrupting the process of reproduction system, increasing the risk of endometriosis.
2. Weakened immune system
Xenoestrogen is toxic to our body. Overdosing of xenoestrogens not only disrupts the production of natural estrogen from our body, it also exhibits the forming of free radicals and weakens our immune system to fight against any bacteria and virus as well as implanting endometrial cells in the wrong parts of our body.
3. Exacerbated by food intake
Since we already known that xenoestrogen is the result of man made harmful products. Overload xenoestrogen through food intake may exacerbate high level of estrogen being produced from the body resulting in hormone imbalance as well as increasing the risk of endometriosis.
4. Stimulating coelomic metaphasia
As we know, xenoestrogen toxifies our body and disrupts the normal function of cell's development in our body increasing the risk of some of the peritoneal cells develop into endometrial cells according to the coelomic metaphasia theory.
5. Hormonal Imbalance
Xenoestrogen increases the production of estrogen in a woman's body causing hormone imbalance resulting in disruption of menstrual cycle causing menstrual cramps as well as promoting the growth of endometrial cells in the abdomen.
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V. Environmental toxins
1. Stimulating the production of bad estrogen
Environmental toxins enter our body stimulating the production of certain hormones. It may cause high levels of estrogen during menstrual cycle elevating the activity of endometriosis.
2. Weakening immune system
Our immune system guards our body against the invasion of bacteria and virus, and regulates the normal function of our body. Weakened immune system might allow the forming of free radicals and other implantations. If the immune system can destroy endometrial cell adhere to the abdominal wall, causing endometriosis.
3. Inflammation
Environmental toxins cause inflammation in our body. Too much environmental toxins damage our immune and nervous system, weakening the repairing damaged tissue function that allows endometrial implants or adhesion to develop in other parts in the body.
4. Hormonal imbalance
Environmental toxins promote high levels of estrogen during the menstrual cycle causing irregular menstruation that increases the risk of endometrial implants and adhesion.
5. Stimulating coelomic metaplasia
Environmental toxins interfere with the normal function of cellular development causing some peritoneum cells to transform to endometrial cells.
VI. Hormonal imbalance
1. Side effects of hormonal medications
Hormone medication may increase the risk of over-production of certain hormones. In case of endometriosis, the surge of estrogen during menstrual cycle may cause menstrual cramps and other symptoms of menstruation increasing the risk of endometriosis.
2. Xenoestrogens
Xenoestrogens are harmful man-made products that interfere with the production of natural estrogen in a woman's body. Too much xenoestrogen increases symptoms during the mense as well as increasing the risk of endometriosis.
3. Environmental toxins
Environmental toxins cause inflammation and stimulates the production of certain hormones in our body causing hormonal imbalance. Over-production of estrogen during a woman's menstrual cycle increases the risk of endometriosis.
4. Unhealthy diet
Over intake of saturated and trans fat causes an imbalance of omega 3 and omega 6 fatty acids which increases the risk of over-production of estrogen that turns into bad estrogen, resulting in hormonal imbalance as well as increasing the risk of endometriosis.
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VII. iatrogenic origins
1. Birth control pills
Women take birth control pills to prevent pregnancy. Unfortunately, pregnancy may happen without being noticed causing hormonal imbalance that interferes with the normal growth of the fetus in the uterus resulting in some abnormal development of cells. Some cells in the peritoneum develop into endometrial cell within the abdomen causing endometriosis at purity. Also birth control pills, besides contributing to thinning of the endometrial lining, it also cause the blood vessel to dilate, increasing the risk of retrograde menstruation and endometrial implantation leading to endometriosis after the pill has stopped. Study shows that infertility medication causes 57% of women to develop endometriosis.
2. Anti inflammation medication
Certain anti inflammation medications that block the prostaglandins hormone that helps our body respond to inflammation when the body's tissue is damaged and suppresses our body's immune system to prevent organ rejection after organ transplant may increase the risk of endometroisis.
Since endometriosis is treatable and manageable by natural remedies and self help course, if you have endometroisis, please look at the bright side.
I hope this information will help. If you need more information or insurance advices, please follow my article series of the above subject at my home page at:
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For Complete Series of Endometriosis and Everything You Want to Know About Endometriosis
Reading the series of endometriosis articles from endometriosis Part 01 to 35
Reading the series of endometriosis articles from endometriosis Part 36 to 70
Reading the series of endometriosis articles from endometriosis Part 71 to be continued
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